STRATA: Stratification of Asthma Treatment by Breath Analysis
Selecting the right treatment for severe asthma patients by replacing the trial and error approach
OVERVIEW
Replacing a trial and error approach to treatment
Funded by an Innovate UK grant, Owlstone Medical is conducting research into the use of volatile organic compounds (VOCs) in patients’ exhaled breath as a way to select the best treatment.
Too many asthma patients are currently on the wrong medication. In the STRATA programme, Owlstone Medical will adapt our existing disease breathalyzer technology to stratify asthma patients and match them to the correct existing treatments first time. As a result we will bring lasting benefit to patients, minimize costs for the NHS and make a positive impact on the annual toll of 54,000 asthma-related emergency hospital admissions and 1,167 asthma-related deaths. You can download an insightful infographic about STRATA here.
OUR PLAN
Harnessing the information contained in breath
Every time we breath out there are hundreds of volatile organic compounds (VOCs) on our breath. Some of these volatile compounds have the potential to be used to distinguish clinical phenotypes in asthma and predict who will respond to currently available treatments.
With the support of U-BIOPRED
U-BIOPRED is a European consortium (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes) investigating severe asthma. At the 2015 European Respiratory Society Conference they reported how Owlstone Medical’s technology has the potential to be used to stratify asthmatic patients into sub-groups, according to which type of treatment they are most likely to benefit from.
THE TEST
Accelerating time to deployment
Through combining the ReCIVA Breath Sampler and FAIMS technology, Owlstone Medical is uniquely positioned to provide a clinically-deployable solution for asthma stratification.
In future, the STRATA breath test will be conducted in a hospital, the samples sent to a central laboratory and results returned electronically.
