Orna Barash at the Breath Biopsy Conference 2021
Sampling and Analysis session - Outcomes and conclusions from clinical performance evaluation of using VOCIDTM for the detection of COVID-19 in exhaled breath (20min)
The Breath Biopsy Conference 2022 is scheduled for 1st-3rd November. Click the button to express interest in the next Breath Biopsy Conference:
Talk Abstract:
The mitigation of the COVID-19 pandemic greatly depends on early detection of asymptomatic and symptomatic infected individuals. Thus, there is a rising demand for quick, easy to use, point-of-care tests. A potential tool for such rapid screening is based on Volatile Organic Compounds (VOCs) measurement and analysis comprising NanoScent’s VOCIDTM breath test. NanoScent’s breath test was designed to identify a ‘fingerprint’ of disease-specific VOCs for COVID-19 in less than one minute. The core of NanoScent’s technology is based on proprietary chemoresistor nanoparticle sensors that react differently to distinct VOC fingerprints, allowing for the individual identification of diseases such as COVID-19, as well as other health-related states of interest. While there are several considerable challenges to portable scent recognition technology, mostly due to environmental effects and sensor drift, the VOCIDTM breath test was successfully deployed in a major hospital in Israel. This feasibility study, including 152 individuals (45 PCR-positive and 107 PCR-negative patients), resulted in 76% sensitivity and 75% specificity for identification of SARS-CoV-2. We also explored three breath sampling methods for their effectiveness, as well as the timeframe necessary between breath collection and before exposure to the sensor. This study proved that the VOCIDTM test has a potential for mass screening of COVID-19 and helped shape future development plans for improving the NanoScent system as a fast, reliable and sensitive tool for upper respiratory tract viral infections.
Speaker Biography:
Orna Barash works as VP Clinics at NanoScent. She previously worked as a researcher and teacher assistant at Technion, Israel Institute of Technology, and as a research assistant at the Marie Curie Excellence Center for Artificial Olfactory Systems. Orna has a PhD from the Laboratory for Nanomaterial-based Devices (LNBD), Department of Chemical Engineering, Technion – Israel Institute of Technology.
The Breath Biopsy Conference 2022 is scheduled for 1st-3rd November. Click the button to express interest in the next Breath Biopsy Conference: