Poster Audio: Analyzing Metabolic Responses to a Standardized Meal Challenge Using The Breath Biopsy OMNI Platform

Volatile organic compounds (VOCs) in exhaled breath can reflect metabolic responses, and understanding the intricate connection between human metabolism and different physiological states in a non-invasive manner is crucial for future clinical applications. In our study, we aimed to elucidate the impact of dietary intake on exhaled breath VOCs, highlighting the capability of our OMNI® breath collection and analysis platform to detect metabolically relevant volatile compounds.

Non-invasively detecting diet-induced metabolic changes in breath VOCs will facilitate future disease-related research. Several microbiome-related and exposure compounds (deriving from food or flavoring) were found to change between fed and fasted participants in this study. Short-chain fatty acids (SCFAs) such as butyric, propionic, and acetic acid showed an upward trend following the consumption of food.

We recently presented this work at the American College of Gastroenterology (ACG) conference, and you can view our presentation below. If you are interested in finding out more, or meeting us at a conference, please get in touch.

We also presented this study at the 2024 Breath Biopsy Conference, which you can view here.