In developed countries, poor diet and low exercise have driven the rise in cardiometabolic disease incidence.
There is therefore a critical need for earlier detection of cardiometabolic disease when lifestyle changes and therapeutics can be effectively deployed, and the number of patients experiencing severe symptoms reduced.
We are developing a breath test capable of detecting liver disease early before any symptoms show, involving the use of an Exogenous Volatile Organic Compound (EVOC®) Probe known as limonene to probe the function of the liver. Our work in this area has been highly successful and indicates that breath testing in this way may be a suitable test to screen for liver disease in children and adults.
Case Studies
A detailed look at some of the research studies investigating biomarkers for different types of cardiovascular & metabolic diseases.
Limonene as a Diagnostic Breath Test for Cirrhosis
Breath biomarkers show potential for diagnosing and staging kidney disease
FURTHER READING
Other recommended reading:
- DOCUMENT: Quick Start Guide: Incorporate Breath Analysis into Liver Disease Research
- PAPER: EVOC Probes combined with dynamic breath testing shows excellent diagnostic performance for cirrhosis and reveals signs of portal hypertension
- POSTER: Pre-clinical in vitro VOC analysis to identify biomarker candidates for chronic liver diseases detection – A Breath Biopsy study.
- PAPER: Breath Biopsy to Identify Exhaled Volatile Organic Compound Biomarkers for Liver Cirrhosis Detection.
- WEB PAGE: Liver Breath Analysis (LIBRA®) – Our non-invasive breath test being developed to detect liver cirrhosis earlier.
Blog
Articles published on our blog related to cardiovascular & metabolic diseases.
Download the Breath Biopsy Guide to learn about breath biomarkers and their applications
