Respiratory Diseases

Breath biomarkers could lead to non-invasive detection and monitoring for respiratory diseases

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Publication: Biomarkers of stress in lungs

A study of ultramarathon runners used Breath Biopsy to uncover markers of physical lung stress and injury caused by extreme exercise.

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Quick Start Guide: Incorporate Breath Analysis into Respiratory Disease Research

Read our short document detailing the powerful potential of breath analysis in respiratory disease research, what data we have, and how Owlstone Medical can help.

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Whitepaper: Examining candidate breath biomarkers for kidney disease

Application of Breath Volatile Organic Compounds (VOCs) in Asthma

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Case study: using the VOC Atlas for biomarker development

Breath VOC biomarkers for Cystic Fibrosis – steps towards the development of bacterial infection biomarkers for clinical use

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Chronic respiratory diseases affect over 500M people worldwide and the annual cost of treatment in the US alone is almost $60B.

Although these diseases are common, diagnosis of respiratory diseases is complex as the symptoms experienced overlap considerably, and are driven by multiple subtypes with different underlying biology. 

Breath is in direct contact with the respiratory tract, and so is especially enriched for volatile organic compounds (VOCs) originating from respiratory processes. Breath therefore offers a unique roster of potential biomarkers that can be collected non-invasively. Volatile compounds in exhaled breath have repeatedly shown promise in differentiating respiratory disease subtypes such as asthma. Some of these VOCs originate directly from the underlying inflammatory responses that cause these diseases, making them especially reliable indicators for respiratory disease diagnosis. 

Case Studies

A detailed look at some of the research studies investigating biomarkers for different types respiratory diseases.

FURTHER READING

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Blog

Articles published on our blog related to respiratory diseases.

The Early Detection of IPF Using Breath Analysis
Breath Analysis: A Game-Changer in Early Invasive Aspergillosis Detection?
The potential role of VOCs in detecting and treating lung cancer
Leaders in the Field: Renelle Myers on translating breath into the clinic
Working with University of Manchester to develop new asthma diagnostics
The Early Detection of IPF Using Breath Analysis
Breath Analysis: A Game-Changer in Early Invasive Aspergillosis Detection?
The potential role of VOCs in detecting and treating lung cancer
Leaders in the Field: Renelle Myers on translating breath into the clinic
Working with University of Manchester to develop new asthma diagnostics

Download the Breath Biopsy Guide to learn about breath biomarkers and their applications